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What Is Pellet Therapy?

Pellet therapy is the most convenient and effective method of hormone replacement available. It has been thoroughly documented and researched in medical journals since 1939 and involves the simple and painless insertion of bio-identical hormone pellets under the skin.


Once the pellet is inserted, a steady, low dose of natural hormones flows directly into the blood stream whenever the body needs is. This gives the body the ability to control the release of the hormones just as it did when the ovaries and testicles were working normally. The SottoPelle® method insures an individual dose for each patient.

SottoPelle® Bio Identical Pellet - North Florida Hormone Therapy

I thought "hormones" were only important for women prior to menopause? 

This a common belief. The truth is that all women need balanced hormones to live healthy lives. As a woman ages, her hormone levels decline and become imbalanced. This is often accompanied by a multitude of distressing symptoms such as hot flashes, mood swings, fatigue, weight gain, lack of libido, and memory loss. By replacing the hormones she is missing with bio-identical pellet hormone therapy, utilizing the SottoPelle® method, her symptoms can disappear.


Of course, men also experience waning hormones as they age. "Andropause," as male menopause is called, can cause a host of symptoms such as chronic fatigue, loss of energy, low sex drive, diminished physical agility, memory loss, and increased belly fat. The good news is that hormone therapy, utilizing the SottoPelle® method, can return a man to healthy levels of testosterone and help him get back on the road to vitality

As a woman, why do I need estrogen and testosterone?

Estrogen is the most important hormone a woman has, protecting her from heart disease, stroke, osteoporosis and Alzheimer’s disease. Synthetic estrogen taken orally does not offer these universal benefits. Estrogen also promotes serotonin production which reduces anxiety, depression, moodiness and anger.


Testosterone gives a woman her mental clarity, libido and muscle tone and mass. Without it, women often complain of mental confusion, weight gain and poor muscle growth even with regular exercise.

Why is testosterone important for men?

Testosterone is central to a man’s well-being. Without it, fatigue, anxiety, depression, loss of mental clarity and libido occur. Furthermore, a deficiency in testosterone may lead to prostate problems, poor sexual performance, poor memory, and loss of muscle tone and mass. Additionally, men with low testosterone have a shorter life span and three times the chances of developing Alzheimer’s.

What does bio-identical mean?

Biologically identical means that the hormones found in the SottoPelle® pellets are the exact same ones as produced by the human body. Biologically identical hormones are not synthetic, simulations or replicas. SottoPelle® pellets are compounded according to the highest industry standards, using the best quality botanical ingredients available including yam and natural plant-based ingredients which possess the exact hormonal structure of human hormone.

What is the first step in the pellet therapy process?

After Dr. Sekine has evaluated your hormone levels and determined your dose, he will place the necessary hormone pellets painlessly under the skin, typically in the buttocks area of the body. The procedure uses a mild, local anesthetic and takes less than five minutes.

How long will it take for pellet therapy to start working?

Most female patients report that they begin to experience improvement within several days of receiving their pellets, but may take up to three weeks to feel the full effects. Testosterone pellets may take two weeks to express their benefits for men and women.

Why SottoPelle® Pellet Therapy?

Since 1992, pellet hormone therapy, as used by SottoPelle® method, has helped thousands of men and women achieve the natural balance of hormones their bodies need to maintain optimum well-being. Our patients report that they feel fantastic again!


Some of the benefits include:


  • Restored or increased sexual desire

  • Consistency in moods

  • Relief from anxiety and depression

  • Increased mental clarity, focus and memory

  • Greater capacity for getting the body in shape and a shorter recovery time from exercise

  • Improved energy, exercise tolerance, and muscle mass

  • Better quality of life

If you have any questions about whether pellet therapy is right for you, please call 904-262-5333 or fill our our online contact form.

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